Sputum “IL‐5, IL‐17A, IL‐25‐high” pattern is associated with uncontrolled asthma and worse lung function

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Sputum “IL-5, IL-17A, IL-25-high” pattern is associated with uncontrolled asthma and worse lung function

Results The “IL-5-high” asthma profile (n=13) merged with the “IL-25-high” (10/13) and surprisingly also with the “IL-17A-high” (11/13) profile. A sputum “IL-25-high” profile was even restricted to patients with an “IL-5-high” profile. Only a minority of “IL-5-high” patients were found to be “IL-4-high” (n=6), whereas 17 other patients had an “IL-4-high” profile without being “IL-5-high”. Patie...

متن کامل

Chronic cough and sputum production are associated with worse clinical outcomes in stable asthma.

BACKGROUND Chronic cough and sputum production (chronic mucus hypersecretion) is a poorly described clinical feature of asthma. Our objective was to identify clinical, immunological and computed tomography (CT) measures of airway wall dimensions associated with these symptoms in smokers and never smokers with asthma. METHODS Cross-sectional data was analysed from 120 smokers and never smokers...

متن کامل

Individual-level socioeconomic status is associated with worse asthma morbidity in patients with asthma

BACKGROUND Low socioeconomic status (SES) has been linked to higher morbidity in patients with chronic diseases, but may be particularly relevant to asthma, as asthmatics of lower SES may have higher exposures to indoor (e.g., cockroaches, tobacco smoke) and outdoor (e.g., urban pollution) allergens, thus increasing risk for exacerbations. METHODS This study assessed associations between adul...

متن کامل

Low socioeconomic status is associated with worse lung function in the Danish cystic fibrosis population

Low socioeconomic status is associated with worse lung function and greater risk of death in people with cystic fibrosis (CF) in the UK and USA, but there are no population level studies from other countries [1–4]. A feature of previous analyses of inequalities in lung function in CF by socioeconomic status has been the identification of a lung function deficit in more disadvantaged children, w...

متن کامل

Variation in lung function is associated with worse clinical outcomes in cystic fibrosis

OBJECTIVE To determine whether the variation in lung function over one year is associated with worse clinical outcomes, as well as with a decline in lung function in the following years, in patients with cystic fibrosis (CF). METHODS This was a retrospective study involving CF patients (4-19 years of age), evaluated over a three-year period. We evaluated demographic characteristics, chronic P...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Clinical and Translational Allergy

سال: 2013

ISSN: 2045-7022,2045-7022

DOI: 10.1186/2045-7022-3-s1-o3